中国美容医学杂志2001，Vol.10Issue(2)：100-102,3.
苦参碱对人增生性瘢痕成纤维细胞超微结构的影响
THE FIBROBLASTIC ULTRASTRUCTURE INFLUENCE OF MATRINE ON HYPERTROPHIC SCAR
汤苏阳 1黄高升 1蔡宝仁2
作者信息
- 1. 第四军大学病理教研室
- 2. 沈阳军区205医院
- 折叠
摘要
Abstract
Objective:To investigate the influence of fibroblastic ultrastructure after applying the matrine on the hypertrohic scar. Methods: The fibroblasts were cultured in vitro, to observe the morphology changes of cell by Electron microscopy (SEM and TEM)after applying matrine. Results:Compared with the untreated fibroblast from hypertrophic scar, the rough endoplasmic reticulums were decreased, the ribosome were appeared degranulation and depolymerization and lysosomes were lncreased respectively. The nuclear chromations were condensed to gather to the side of nuclear membranes. Conclusion:Mat could inhibit the function of hypertrophic fibroblasts and induce the apoptosis of hypertrophic fibroblasts and changed the altrastructural significantly.关键词
苦参碱增生性瘢痕成纤维细胞超微结构分类
医药卫生引用本文复制引用
汤苏阳,黄高升,蔡宝仁..苦参碱对人增生性瘢痕成纤维细胞超微结构的影响[J].中国美容医学杂志,2001,10(2):100-102,3.
