四川医学2009,Vol.30Issue(7):1002-1003,2.
阿维A联合窄谱中波紫外线治疗寻常型银屑病疗效观察及血清透明质酸的测定
Observation of clinical effect and changes of serum hyaluronic acid in psoriastic patients treated with etretinate and narrow-band ultraviolet B
摘要
Abstract
Objective To observe the therapeutic efficacy of etretinate and narrow-band ultraviolet B(NB-UVB)for pso-fie.sis and to investigate the changes of hyaluronic acid in serum. Methods 40 cases of psoriasis vulgaris were treated with etreti-hate and NB-UVB irradiation which was performed 3 times a week ,totally for 20 times. The clinical efficacy and adverse reactions were observed and serum hyalurunic acid level were measured before and after treatment in patients. Results The total clinical efficiency was 92.5%. The level of hyaluronic acid in serum decreased after treatment which was higher than normal controls be-fore treatment. The difference was statistically significant(P<0.05). Conclusion Etretinate and NB-UVB show a good effect on treatment of psoriasis uulgaris and can reduce the level of serum hyaluronic acid.关键词
寻常型银屑病/窄谱中波紫外线/阿维A/透明质酸Key words
psoriasis vulgaris/ narrow-band ultraviolet B / etretinate/ hyaluronic acid分类
医药卫生引用本文复制引用
周敏,丰世科,陈金,段西凌,陈琦,陈学军..阿维A联合窄谱中波紫外线治疗寻常型银屑病疗效观察及血清透明质酸的测定[J].四川医学,2009,30(7):1002-1003,2.基金项目
四川省卫生厅科研项目(编号:070369) (编号:070369)