河北医学2009，Vol.15Issue(9)：1015-1018,4.
血浆N-末端脑利钠肽在慢性肾脏病非透析患者合并心力衰竭中的临床意义
The Clinical Significance of Plasma N-Terminal Brain Natriuretic Peptide Level in Chronic Kidney Disease Patients Accompanied by Heart Failure without Dialysis
郭旭武 1陈楚鹏 1王奕忠 1王良玉1
作者信息
- 1. 中山大学附属汕头医院,广东,汕头,515031
- 折叠
摘要
Abstract
Objective: To investigate relationship between the plasma N-Terminal brain natriuretie peptide (NT-proBNP) level and chronic heart failure (CHF) in chronic kidney disease (CKD) patients without dialysis. Method: The electrochemiluminescenee assay and the complete automatic biochemistry analyzer was respectively used to dectect NT-proBNP level and creatinine, urea nitrogen level in 59 cases chronic heart failure was significantly higher than that in patients with non-heart failure group [(5927.8±9628.value could be used to diagnose CHF with sensitivity of 93.2% (55/59) and specificity 90.0% (9/10) ;multiple regression analysis showed that LVEF and GFR are the independent factors to NT-proBNP level.Conclusion: There was significantly correlated ( r=-0.407, P<0.01) between NT-proBNP levels and heart function and kidney function in CKD patients without dialysis , NT-proBNP levels can be used to evaluate the CKD patients without dialysis as an indicators of cardiac function.关键词
脑利钠肽/心力衰竭/肾透析/慢性肾脏病Key words
Brain natriuretic peptide/Heart failure/Renal dialysis/Chronic kidney disease分类
医药卫生引用本文复制引用
郭旭武,陈楚鹏,王奕忠,王良玉..血浆N-末端脑利钠肽在慢性肾脏病非透析患者合并心力衰竭中的临床意义[J].河北医学,2009,15(9):1015-1018,4.
