中国中西医结合杂志2001,Vol.21Issue(2):102-104,3.
抗炎灵对腹部外科全身炎性反应综合征和多器官功能不全综合征患者细胞因子和C-反应蛋白作用的研究
Study for Effect of Kangyanling on Cytokine and C-Reactive Protein in Patients of Systemic Inflammatory Reaction Syndrome and Multi-Organ Dysfunction Syndrome after Abdominal Surgery
摘要
Abstract
Objective: To observe the clinical effect and mechanism ofKangyanling (KYL) in treating patients with systemic inflammatory reaction syndrome and multi-organ dysfunction syndrome (SIRS/MODS) after abdominal surgery. Methods: Eighty-two patients of SIRS/MODS after abdominal surgery were divided into two groups according to admission time, the KYL treated group (n=35) and the control group (n=47). The levels of serum C-reactive protein (CRP), plasma tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) were measured at the 1st, 3rd and 7th day post-operationally. Results: The levels of CRP, TNF-α and IL-6 decreased gradually after surgical operation in both groups, but the reducing velocity was shorter in the KYL group than that in the control group, so the comparison of the levels in the two group showed significant difference on the 3rd day after operation (P<0.05). Conclusion: KYL could inhibit the release of inflammatory mediator and relieve the inflammatory response so as to treat post-operational SIRS/MODS effectively.关键词
抗炎灵 腹部外科 细胞因子 C-反应蛋白 全身性反应综合征 多器官功能不全综合征分类
医药卫生引用本文复制引用
陈哲宇,齐清会..抗炎灵对腹部外科全身炎性反应综合征和多器官功能不全综合征患者细胞因子和C-反应蛋白作用的研究[J].中国中西医结合杂志,2001,21(2):102-104,3.基金项目
本项目为天津市自然科学基金课题(No.983609111) (No.983609111)