中华医学杂志（英文版）2001，Vol.114Issue(10)：1039-1042,4.
溶栓治疗对急性下壁心肌梗塞伴房室传导阻滞发生的影响
Atrioventricular block complicating inferior acute myocardial infarction treated with thrombolytic therapy
摘要
Abstract
Objective To investigate the influence and mechanism of incidence of atrioventricular block (AVB) treated
with thrombolytic therapy in acute inferior myocardial infarction (AIMI).
Methods A total of 46 patients with AIMI were divided into the thrombolytic group (n = 23) and the non
thrornboytic group (n = 23). Intravenous or intracoronary urokinase was given to the former group. We
observed the advancing courses of AVB, and further assessed the relationship between occurrence of AVB
and stenosis of infarct-related artery (IRA) with coronary angiography.
Results Two cases died of Ⅲ o AVB in the non-thrombolytic group, but none was found in the thrombolytic
group. The occurrence rate of AVB was similar in both groups; but that of Ⅲ ° AVB was much lower in the
thrombolytic group (4 cases) than that in the non-thrombolytic group (11 cases, P ＜ 0.05), and the
duration of AVB decreased from 201 ± 113 hours to 102±60 hours after thrombolytic therapy ( P＜0.01 ),
which was mainly due to the decrease of AVB in the vanishing interval, but not in the developing interval.
The coronary angiography demonstrated that there were an increasing reperfusion flow and a decreasing
coronary stenosis of the infarct-related artery after thrombolytic therapy.
Conclusion Thrombolytic therapy can reduce the incidence of severe AVB, shorten its duration and
decrease the mortality by increasing the coronary reperfusion flow in the patients with AIMI.关键词
下壁心肌梗塞房室传导阻滞溶栓治疗再灌注冠状动脉造影分类
医药卫生引用本文复制引用
陈士良,冯胜强,张清华..溶栓治疗对急性下壁心肌梗塞伴房室传导阻滞发生的影响[J].中华医学杂志（英文版）,2001,114(10):1039-1042,4.
