现代妇产科进展2001,Vol.10Issue(2):105-107,3.
小剂量顺铂化疗联合放射治疗对实验性人子宫颈癌传代细胞增效作用的研究
Study of low dose cisplatin with radiotherapy enhancing the experimental human cervicalcarcinoma passage cells sensitivity produced by radiation
姜玉华 1程玉峰 1乔乃安 1梁业民 1胡立宽 1刘慧忠 1章晓梅 1赵潍萍1
作者信息
摘要
Abstract
Objective:To study low dose cisplatin with radiotherapyenhancing the experimental human cervical carcinoma passage cells(HeLa cells)radiosensivity.Methods:The nude mice were divided into four groups(control group,radiotherapy only,chemotherapy only,radiotherapy and chemotherapy)randomly.The size of tumors was measured separately,and tumor growth curves weredrafted.Results:Radiotherapy only and chemotherapy can inhibitethe growth of tumor. There were obvious differences about the tumor size betweenradiotherapy plus chemotherapy and other groups.The rates of tumor growth inhibition were 69.48%,77.31%,90.24% respectively. Conclusions:Low dose cisplatin can obviously enhance the sensitivity of radiotherapy.This providestheoretical basis for the clinical use of low dose cisplatin with radiotherapy.关键词
顺铂/放射疗法/化学疗法,辅助/动物,实验/HeLa细胞分类
医药卫生引用本文复制引用
姜玉华,程玉峰,乔乃安,梁业民,胡立宽,刘慧忠,章晓梅,赵潍萍..小剂量顺铂化疗联合放射治疗对实验性人子宫颈癌传代细胞增效作用的研究[J].现代妇产科进展,2001,10(2):105-107,3.