摘要
Abstract
Objective To investigate the prevalence, clinical features and the law of development of undifferentiated spondylarthropathies (uSpA). Methods Within five years, 127 uSpA patients were registered in rheumatology outpatient clinic of Second Hospital Shanxi Medical University. The clinical, laboratory and follow-up datas of uSpA patients were collected and analyzed. Results (1) The male female ratio is 1.8: 1, and the female late onset. (2) The chief symptoms of 127 uSpA patients were lumbar and back pain (93.7%) and joints pain (96.0%). (3) Female patients lower back pain was significantly higher than that of the first male (P < 0.05). Some patients with region eoxae, hip and heel or other attachment sites pain onset, there first rates of men were higher than female (P < 0.05). (4) Seven eases of hand joints involvement as the first symptoms were women. (5) The positive rate of family history and HLA-B27 were 42.5% and 52.8%, there was no significant difference between male and female. (6) The sensitivity of sacroiliac joints CT in the diagnosis of uSpA was higher than X-ray, the two positive rates of Sacroiliitis were 75.0% (78/104), 60% (51/85). The emergence rates of sacroiliac joints damage of male was higher than women (P < 0.05). (7) In five years 56 cases developed to 18 cases ankylosing spondylitis (AS), 1 enteropathic arthropathy, 1 psoriatic arthritis (PsA), 20 uSpA, 16 cases with symptomatic disappear. In 18 cases confirmed AS there were 13 male patients, accounting for 72.2%. In 5 years the positive rates of all sacroiliac joint CT signs had increased, the grade Ⅱ sacroiliac joint destruction progress evidently, the destruction positive rates of the examinations in initial and 5 year later were 3.6% and 48.2%. Conclusions uSpA were a group of a variety of spondyloarthropathy, which had a genetic predisposition. The sacroiliac joint involvement of men was more serious than women. Some patients can progress to ankylosing spondylitis, psoriatic arthritis and enteropathic arthropathy, and other SpA. Close follow-up on the patients and regular line sacroiliac joint CT examination conduce to early diagnosis.关键词
未分化脊柱关节病/诊断/随访Key words
undifferentiated spondyloarthropathies/diagnosis/follow-up分类
医药卫生
