林产化学与工业2006，Vol.26Issue(1)：109-115,7.
原花色素在生物体内的吸收和代谢与生物可利用性
Proanthocyanidins: Absorption, Metabolism and Bioavailability
摘要
Abstract
Proanthocyanidins ( PAs), as a predominant group of both flavonoids and polyphenols, are less studied than other simpler compounds due to their large molecular size, complicated structure and polymeric nature, though they play major roles in both human diet and animal forages and have noticeable health effects. In this review, the absorption and bioavailability of PAs are compared among catechin (CC) monomers, PA dimers/trimers and larger PA oligomers. The metabolic fate of PAs is summarized, and one possible mechanism of PA degradation in vivo is discussed, based on some evidence of a preliminary depolymerization. Regarding to various physi ological potential of PAs, plasma circulation and cellular uptake of these compounds and their metabolites are also briefly referred. These help to figure out to what extent the monomers, dimers/trimers, larger PA polymers, or their metabolites directly contribute to the multiple biological effects in vivo, so as to demonstrate the health effects of PAs, and elucidate the relevant mechanisms.关键词
原花色素/原花青素/代谢/生物可利用性Key words
proanthocyanidins/procyanidins/metabolism/bioavailability分类
化学化工引用本文复制引用
罗欣,姚开,贾冬英,何强..原花色素在生物体内的吸收和代谢与生物可利用性[J].林产化学与工业,2006,26(1):109-115,7.基金项目
国家自然科学基金资助项目(20472058) （20472058）
