耳鼻咽喉-头颈外科2001，Vol.8Issue(2)：110-113,4.
三半规管阻塞与迷路切除术后前庭功能动态变化
Vestibular compensation after triple semicircular canal occlusion and labyrinthectomy
殷善开 1张英 1黄艳艳 1张茂椿 1李漫娜2
作者信息
- 1. 上海第二医科大学附属上海市第六人民医院
- 2. 上海市听力测试中心
- 折叠
摘要
Abstract
Objective:To evaluate the difference of vestibular compensation between triple semicircular canal occlusion(TCO) and labyrinthectomy(LE)in guinea pigs.Material and Methods:TCO was performed on 8 guinea pigs,while LE was did on 7 guinea pigs.Behavior and ENG were recorded in detail preoperatively and repeatedly up to one month postoperatively according to the experiment design.Results:There was spontaneous nystagmus towards the nonoperated side on the first postoperative day and nystagmus absence during sinusoidal angular acceleration stimuli on the operated side was observed in all the animals.All the animals displayed head tilt towards the operated side (right)and an unsteady gait towards the right along the vertical axis after surgery,while the animals performed LE rolled towards the operated side.On the 3rd postoperative day,faint nystagmus appeared on the operated side,but the left and right nystagmus was significantly asymmetrical.The left and right nystagmus still remained asymmetrical on the 5th and 10th day postoperatively.From the 15th postoperative day,left and right nystagmus returned symmetrical in the animals performed TCO,while left and right nystagmus returned symmetrical only at the pendular amplitude of 120°,150°,180°,in the animals performed LE up to 30th postoperative day.There was a significant reduction of nystagmus to the operated side at the Pendular amplitude of 60°and 90° one month after the LE and there was 3 animals still displayed head tilt towards the operated side.Conclusion: the animals compensated faster and more completely after TCO than LE.关键词
前庭功能试验/半规管/豚鼠/迷路切除术分类
医药卫生引用本文复制引用
殷善开,张英,黄艳艳,张茂椿,李漫娜..三半规管阻塞与迷路切除术后前庭功能动态变化[J].耳鼻咽喉-头颈外科,2001,8(2):110-113,4.
