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Detection of recent HIV-1 infections among men who have sex with men in Beijing during 2005-2006

LI Shen-wei ZHANG Xiao-yan LI Xin-xu WANG Min-jie LI Dong-liang RUAN Yu-hua ZHANG Xiao-xi SHAO Yi-ming

中华医学杂志(英文版)2008,Vol.121Issue(12):1105-1108,4.
中华医学杂志(英文版)2008,Vol.121Issue(12):1105-1108,4.

Detection of recent HIV-1 infections among men who have sex with men in Beijing during 2005-2006

Detection of recent HIV-1 infections among men who have sex with men in Beijing during 2005-2006

LI Shen-wei 1ZHANG Xiao-yan 1LI Xin-xu 1WANG Min-jie 1LI Dong-liang 2RUAN Yu-hua 1ZHANG Xiao-xi 2SHAO Yi-ming1

作者信息

  • 1. State Key Laboratory for Infectious Disease Prevention and Control,National Center for AIDS/STD Control and Prevention,China CDC,Beijing 100050,China
  • 2. Chaoyang District Center for AIDS/STD Control and Prevention,Beiiing 100021,China
  • 折叠

摘要

Abstract

Background Men who have sex with men (MSM) have become one of the most risky populations for HIV infection in China.Though several cross-sectional sero-prevalence studies have been conducted.the annual HIV incidence remains unknown in this population.Methods We applied IgG-capture BED-enzyme immunoassay (BED-CEIA) to define the recent HIV-1 infections among MSM in Beijing in the years 2005 and 2006 and the annual HIV incidence was estimated.Results Overall,1067 MSM samples were collected,including 526 samples in the year 2005 and 541 in 2006.In 2005,0f 17 HIV seropositive samples.7 were identified as recent HIV-1 infections and the estimated HIV infection incidence was 2.9% per year (95%CI,0.8%-5.0%).In 2006,of 26 HIV seropositive samples,9 were identified as recent HIV-1 infections and the estimated annual incidence was 3.6% (95%CI,1.3%-5.9%),which was 0.7% higher than that in 2005.Individuals engaging in male group sexual intercourse (5.17% vs 0.87%,P=0.019) and having receptive anal sexual intercourse more than five times (2.79% vs 0.33%,P=0.047) in the past 6 months significantly increase the risk of being infected by HIV-1.Conclusions A high level of annual HIV-1 infection incidence was observed among MSM in Beijing for the consecutive years 2005 and 2006 with a continuous increasing trend.The rising incidence and related high risk behavior among MSM alarmed the health authorities and calls for more effective intervention strategies among this population.

关键词

HIV-1/men who have sex with men/HIV incidence/IgG-capture BED-enzyme immunoassay

Key words

HIV-1/men who have sex with men/HIV incidence/IgG-capture BED-enzyme immunoassay

分类

医药卫生

引用本文复制引用

LI Shen-wei,ZHANG Xiao-yan,LI Xin-xu,WANG Min-jie,LI Dong-liang,RUAN Yu-hua,ZHANG Xiao-xi,SHAO Yi-ming..Detection of recent HIV-1 infections among men who have sex with men in Beijing during 2005-2006[J].中华医学杂志(英文版),2008,121(12):1105-1108,4.

基金项目

This study was supported by a grant from the Ministry of Science and Technology of China (No.2004BA719A01). (No.2004BA719A01)

中华医学杂志(英文版)

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