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首页|期刊导航|西安医科大学学报|豚鼠心脏表面神经节丛SP、CGRP及VIP 的免疫组织化学研究

豚鼠心脏表面神经节丛SP、CGRP及VIP 的免疫组织化学研究

马东亮 李月英 王唯析 胡海涛 赵志英 袁秉祥

西安医科大学学报2001,Vol.22Issue(1):11-13,3.
西安医科大学学报2001,Vol.22Issue(1):11-13,3.

豚鼠心脏表面神经节丛SP、CGRP及VIP 的免疫组织化学研究

Immunohistochemical study on SP,CGRP and VIP in superficial ganglial plexus of the guinea pig heart

马东亮 1李月英 1王唯析 1胡海涛 1赵志英 2袁秉祥3

作者信息

  • 1. 西安交通大学医学院人体解剖学教研室,
  • 2. 内蒙古包头医学院解剖学教研室
  • 3. 西安交通大学医学院药理学教研室
  • 折叠

摘要

Abstract

Objective To investigate the distribution and the chemicalproperties of three predominant superfical ganglial plexus which are the right atrial ganglial plexus(RAGP),the dorsal atrial ganglial plexus(DAGP) and the ganglial plexus between aorta and pulmonary artery(A-PGP) in the heart.Methods The study was performed concering the neurons and fibers of SP,CGRP and VIP-immunoreactive(IR) substance in three predominant superfical ganglial plexus of the guinea pig heart by immunohistochemical ABC method and observed by light microscope.Results The SP-IR and CGRP-IR neurons could not be found in the above-mentioned ganglial plexus.But SP-IR fibers distributed sparsely,CGRP-IR fibers were more densely than SP-IR fibers,especially A-PGP.The population of VIP-IR neurons and fibers were most dense and interweaved ganglial plexus.Conclusion There were actually SP,CGRP and VIP in three predominant superfical ganglial plexus of the guinea pig heart and the three peptides could possibly modify the activities of myocardiocytes and vessels of heart directly.

关键词

豚鼠/心脏/神经节丛/P物质(SP)/降钙素基因相关肽(CGRP)/血管活性肠肽(VIP)

分类

医药卫生

引用本文复制引用

马东亮,李月英,王唯析,胡海涛,赵志英,袁秉祥..豚鼠心脏表面神经节丛SP、CGRP及VIP 的免疫组织化学研究[J].西安医科大学学报,2001,22(1):11-13,3.

基金项目

国家自然科学基金资助项目( ()

西安医科大学学报

OA北大核心CSCD

1671-8259

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