中国临床药理学与治疗学2007，Vol.12Issue(10)：1122-1129,8.
中药研究开发的挑战
Challenges in research and development of Traditional Chinese Medicines
刘昌孝 1司端运 2谢海棠2
作者信息
- 1. Tianjin State Key Laboratory of Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
- 2. Anhui Provincial Center for Drug Clinical Evaluation, Wuhu 241001, Anhui, China
- 折叠
摘要
Abstract
In this review, the author analyzed the challenges in modern research and development of Traditional Chinese Medicine (TCM) products. Chinese traditional and herb drugs have gained interest from the international medical, biomedical and pharmaceutical institutions as potential source of valuable medicinal agents. For the researches and development of TCMs, the first challenge is to evaluate the efficacy, pharmacological properties, action mechanism and active chemical constituents. The second one is to summarize the issues for developing safety research methodologies, to improve the quality and enhance the value of research in TCM and to provide appropriate evaluation methods to facilitate the regulation and registration of TCM products, and the third is to study drug metabolism and pharmacokinetics, and the fourth is to apply new "-omics" techniques and tools in new revolution in drug discovery-development and to impact on modern research of TCM products. This interest is needed to apply modern research on the development and exploration of the promising medical potential resources of Chinese traditional and herbal drugs, especially from medicinal plants.关键词
Traditional Chinese Medicine/ challenge/ research/ development/ efficacy/ safety/ new techniqueKey words
Traditional Chinese Medicine/ challenge/ research/ development/ efficacy/ safety/ new technique分类
医药卫生引用本文复制引用
刘昌孝,司端运,谢海棠..中药研究开发的挑战[J].中国临床药理学与治疗学,2007,12(10):1122-1129,8.
