临床与实验病理学杂志2001，Vol.17Issue(2)：113-116,4.
皮下脂膜炎样T细胞淋巴瘤的病理分析及基因诊断
Clinicopathological analysis and genetic diagnosis of subcutaneous panniculitic T-cell lymphoma
李学农 1丁彦青 1朱梅刚 1钟国平 2周军1
作者信息
- 1. 第一军医大学病理学教研室,
- 2. 浙江省鄞县人民医院病理科
- 折叠
摘要
Abstract
Purpose To explore the clinicopathological features of subcutaneous panniculitic T-cell lymphoma(SPTCL) and significances of genetic analysis in the diagnosis. Methods Histopathology, immunohistochemitry and detection of clonal gene rearrangement by PCR were used in 3 cases of subcutaneous panniculitic T-cell lymphoma (SPTCL), which were originally diagnosed as relapsing nodular nonsuppurative panniculitis. Results Three misdiagnostic cases were correctly redefined as subcutaneous panniculitic T-cell lymphoma, with immunophenotype of CD45+,CD45RO+, Mac387－,and clonal TCR-β gene rearrangement. Conclusions Subcutaneous panniculitic T-cell lymphoma has distinctive clinicopathological features. Genetic analysis is an effective method for the diagnosis of SPTCL.关键词
淋巴瘤,T细胞/皮肤肿瘤/基因诊断分类
医药卫生引用本文复制引用
李学农,丁彦青,朱梅刚,钟国平,周军..皮下脂膜炎样T细胞淋巴瘤的病理分析及基因诊断[J].临床与实验病理学杂志,2001,17(2):113-116,4.
