中国病理生理杂志1999，Vol.15Issue(12)：1142-1145,4.
K离子通道在剪切力诱导血管内皮细胞信号转导中的作用
Effects of potassium channel on shear stress - induced signal transduction in vascular endothelial cells
摘要
Abstract
Fluid shear stress play an important role in many physiological and pathophysiological processes of cardiovascular system. Shear stress - induced signal transduction throughout the vascular endothelial cell includes ion channels,G- protein linked receptors, tyrosine kinase receptors and integrins. The one impossible pathway of shear stress - induced signal transduction was biochemical reaction through second messenger, activating protein kinases and cytosolic transcription factors, and then regulating gene transcription . The other pathway was cytoskeletal system. This article reviewed the cellular and molecular mechanism of potassium channel signal transduction resulting from shear stress.关键词
心血管病/钾离子通道/血管内皮细胞/信号转导分类
医药卫生引用本文复制引用
胡金麟..K离子通道在剪切力诱导血管内皮细胞信号转导中的作用[J].中国病理生理杂志,1999,15(12):1142-1145,4.基金项目
国家自然科学基金资助(No 39600040) （No 39600040）
