中国临床康复2004，Vol.8Issue(6)：1182-1183,2.
强迫症患者睡眠特征初步探讨
Preliminary study on sleep features in patients with obsessive-compulsive disorder
庄丽频 1冯永铭 1陈毓麒 1史尧胜 1陈海霞 1丁士炬 1夏颖1
作者信息
- 1. 宁波市康宁医院特检科,浙江省宁波市,315021
- 折叠
摘要
Abstract
BACKGROUND: What is the relationship between sleep parameters of patients with obsessive-compulsive disorder(OCD) and the healthy person and different disorder stages? Disclosing the sleep features in patients with OCD has been the focus of the present study on sleep. OBJECTIVE: To explore and analyze the connection between abnormal sleep and sleep features in patients with OCD. DESIGN: Diagnosis-based case control study. SETTING,SUBJECTS AND METHODS: The 21 cases of OCD selected were hospitalized patients and outpatients of Kangning Hospital in Ningbo City,Zhejiang Province. In the control group,the 20 volunteers were the employees,family members and postgraduate students of the hospital. Polysomnogram(PSG) was performed on the OCD patients and the results were compared with those of the controls. MAIN OUTCOME MEASURES: Parameters of sleep course, sleep structure, and rapid eye movement(REM) were measured in both groups. RESULTS: In OCD patients,all-night waking times and total waking minutes( mean 32.95 times, 73.26min) were more than those of controls( mean 11.46 times, 18.97min) (t=6.55, 1.16, P< 0.01); sleep efficiency fell(mean value in controls and patients was 91.44% and 86.70% , respectively)( t=0.79, P < 0.05); stage 1( S1) percentage of nonrapid eye movement(NREM) reduced(mean value in controls and patients was 6.23% and 4.00% ) (t=0.89, P< 0.05);REM time increased(mean value in controls and OCD group was 18.10 min and 68.86 min,respectively) (t=1.73, P< 0.05).The course of disease was positively correlated with the first latent period of REM sleep(r=0.57, P< 0.01), but negatively correlated with REM sleep time(r=- 0.60, P< 0.01).That is,with the increase of disease course in OCD patients, the first latent period in REM sleep was delayed, but REM sleep time was reduced. CONCLUSION: Abnormal sleep in patients with obsessive-compulsive disorder may be associated with the pathogenesis. 关键词
强迫性障碍/多道睡眠描记术/睡眠分类
医药卫生引用本文复制引用
庄丽频,冯永铭,陈毓麒,史尧胜,陈海霞,丁士炬,夏颖..强迫症患者睡眠特征初步探讨[J].中国临床康复,2004,8(6):1182-1183,2.
