中山医科大学学报2001，Vol.22Issue(2)：122-124,3.
中国汉族群体DXS101位点的多态性
Polymorphism of DXS101 Locus in Chinese Han Population
吕德坚 1李建金 1刘秋玲 1伍新尧1
作者信息
- 1. 中山医科大学法医物证教研室， 广东 广州 510089
- 折叠
摘要
Abstract
【Objective】 To investigate the polymorphism of DXS101 lucus inChinese Han population. 【Methods】 A X-chromosome linked short tandem repeat locus DXS101 was analyzed by PCR following by polyacrylamide gel electrophoresis. Hardy-Weinberg equilibrium was tested and forensic interested value was calculated. 【Results】 Among 147 unrelated females and 150 unrelated males from Chinese Han population, 8 alleles were detected, with frequencies ranging from 0.0133 to 0.2279. Exact tests demonstrated that genotype frequencies in females did not depart from Hardy-Weinberg equilibrium. The unbiased estimating gene diversity was 0.8296, and the discrimination powers for female and male original samples were 0.9474 and 0.8277, respectively. When both mother and her daughter were tested, the probability of excluding a random man as father was 0.8049. 【Conclusion】 This highly discriminatory locus is appropriate for individual identification and paternity testing involving a female child.关键词
串联重复序列/等位基因/X染色体/法医学/多态性现象(遗传)分类
医药卫生引用本文复制引用
吕德坚,李建金,刘秋玲,伍新尧..中国汉族群体DXS101位点的多态性[J].中山医科大学学报,2001,22(2):122-124,3.
