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Characterization of cDNA from the miracidial antigen family of Schistosoma japonicum (Chinese strain)

余传信平山謙二朱荫昌菊池三惠子殷旭仁

中华医学杂志（英文版）2003，Vol.116Issue(8)：1239-1243,5.

Characterization of cDNA from the miracidial antigen family of Schistosoma japonicum (Chinese strain)

余传信 ¹平山謙二 ²朱荫昌 ¹菊池三惠子 ²殷旭仁³

作者信息

1. Department of Science and Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China
2. Department of Molecular Immunologenetics, Institute of Tropical Medicine, Nagasaki University, 1-2.12.8 Sakamoto, Nagasaki 852-8523, Japan
3. Department of Science and Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China
折叠

摘要

Abstract

Objective To identify the egg antigens related to the formation of hepatic granulomas and fibrosis of Schistosomiasis japonica.Methods The egg cDNA library of Schistosoma japonicum (S.japonicum) was constructed and screened by immunological methods with the pooled sera of advanced schistosomiasis patients. The inserted foreign DNA fragments of positive clones were sequenced. The sequence data were analyzed using Wdnasis 2.5 and compared with Genebank data using blast software. Conclusion The cDNA sequence of the miracidial antigen of S.japonicum (Chinese strain) was obtained for the first time.

关键词

Schistosoma japonicum/helminth antigens/cDNA

Key words

Schistosoma japonicum/helminth antigens/cDNA

分类

医药卫生

引用本文复制引用

余传信,平山謙二,朱荫昌,菊池三惠子,殷旭仁..Characterization of cDNA from the miracidial antigen family of Schistosoma japonicum (Chinese strain)[J].中华医学杂志（英文版）,2003,116(8):1239-1243,5.

基金项目

This research was supported by the Science and Research Foundation of Health Bureau of Jiangsu Province. （）

中华医学杂志（英文版）

OAMEDLINESCI

ISSN：0366-6999

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