中国临床康复2003，Vol.7Issue(8)：1241-1242,2.
中药皮肤剥脱剂对豚鼠皮肤损伤的实验研究
A study on skin damage of guinea pigs caused by Chinese medicinal peeling
梁虹 1贺孟泉 2方春红 1熊腊元1
作者信息
- 1. 武汉大学人民医院皮肤科,湖北省武汉市,430060
- 2. 青岛大学化妆品研究室,山东省青岛市,266071
- 折叠
摘要
Abstract
Aim To provide laboratory data of Chinese medicinal peeling(CMP) for clinical application.Methods The experimental drugs were applied on the skin of guinea pigs and the extent of damage caused by different drugs at different time was investigated.Results Three days after the application of the drugs ,the extent of damage of the skin was as follows:(0.22± 0.06) mm in depth( in stratum spinosum and dermal papillae)for CMP group;(0.53± 0.03) mm(in rete ridges)for Baker-Gorden liquid group;(0.12± 0.03) mm(in superficial of stratum corneum) for Jessner liquid group;(0.10± 0.02) mm(stratum corneum) for group of lower concentration of CMP(LCCMP).In groups of Chinese medicinal peeling and Barker-Gorden liquid,solidification and necrosis of keratin and rearrangement of collagenous fibers in upper middle layer of dermis were noted.The rete ridges was infiltrated by neutrophilic granulocytes,lymphocytes and macrophages.No skin damage was found in control group.Conclusion The CMP is superior to chemical peelings in terms of controlling the depth,avoidance of scar formation,accelerating the changes of dead and injured cells of epidermis.关键词
中药/皮肤 /损伤/瘢痕Key words
plants,medicinal/skin/injuries/cicatrix分类
医药卫生引用本文复制引用
梁虹,贺孟泉,方春红,熊腊元..中药皮肤剥脱剂对豚鼠皮肤损伤的实验研究[J].中国临床康复,2003,7(8):1241-1242,2.
