南京医科大学学报（英文版）2006，Vol.20Issue(2)：124-126,3.
Study on Vip protein expression in psoriatic epidermis with the topical treatment of capsaicin ointment
Study on Vip protein expression in psoriatic epidermis with the topical treatment of capsaicin ointment
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作者信息
- 1. Department of Dermatology,Second Hospital of Xi'an Jiaotong University,Xi'an,710004,China;Department of Dermatology,Second Hospital of Xi'an Jiaotong University,Xi'an,710004,China;Department of Dermatology,Second Hospital of Xi'an Jiaotong University,Xi'an,710004,China
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摘要
Abstract
Objective: To investigate the mechanism of capsaicin in treating active psoriasis vulgaris. Methods: VIP protein in active psoriatic lesions before and 30 days after the treatment of capsaicin ointment was detected by immunohistochemistry. Results:There was positive expression of VIP in all layers of psoriatic lesions epidermis (95.5 % ), but after the treatment of capsaicin ointment,there was nearly no expression of VIP protein in epidermis(22.2% ). Conclusion: Capsaicin inhibits proliferation and induces the differentiation of keratinocytes through down-regulating the expression of VIP in psoriatic epidermis.关键词
psoriasis/VIP/capsaicinKey words
psoriasis/VIP/capsaicin分类
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..Study on Vip protein expression in psoriatic epidermis with the topical treatment of capsaicin ointment[J].南京医科大学学报（英文版）,2006,20(2):124-126,3.
