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Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment

徐成丽 朱广瑾 薛全福 祖淑玉

极地研究(英文版)2003,Vol.14Issue(2):124-130,7.
极地研究(英文版)2003,Vol.14Issue(2):124-130,7.

Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment

Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment

徐成丽 1朱广瑾 1薛全福 1祖淑玉2

作者信息

  • 1. Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS), School of Basic Medicine, Peking Union Medical College ( PUMC) , Beijing 100005, China
  • 2. Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS), School of Basic Medicine, Peking Union Medical College ( PUMC) , Beijing 100005, China
  • 折叠

摘要

Abstract

The serum thyroid hormone and plasma catecholamine were examined in 18 male and 2 female members of the Chinese Antarctic Expedition ( who spent the 2000 or 2001 austral winter at the Great Wall Station). The changes of serum thyroid hormone i.e. total thyroxine ( TT4 ) and free T4 ( FT4 ) , total triodothyronine ( TT3 )and freeT3 ( FT3 ), thyroid stimulating hormone (TSH) and plasma eateeholamine,including norepinephrine ( NE), epinephrine (E) and dopamine (DA) , were investigated by Chemoluminescenee Immunoassay (CLIA) and High Performance Liquid Chromatography with electrochemical detection (HPLC-ECD). Samples were taken at different time: (1) 1 day before departure to Antarctica (16th expedition 1999/12/09; 17th expedition 2000/12/06). (2) 1 day after returned to China after living 54 weeks in Antarctica ( 16th expedition 2000/12/25; 17th expedition 2001/12/25 ).Comparing the data of before departure and returned, results showed that there was a significant decrease in the contents of TT4 ( P < 0.01 ) with no significant change in the content of TT3, FT3 and FT4. It was also found that the content of TSH increased significantly (P <0. 001 ); No significant changes of plasma NE and DA were found but the content of E decreased significantly ( P < 0. 001 ). The results indicated that the special Antarctic environment led to a restrain effect on the thyroid function and the level of plasma E in Antarctic expedition members. Both the thyroid and adrenal medulla system were associated in response to the Antarctic systemic stress.

关键词

Antarctica/expedition members/thyroid hormone/catecholamine

Key words

Antarctica/expedition members/thyroid hormone/catecholamine

分类

天文与地球科学

引用本文复制引用

徐成丽,朱广瑾,薛全福,祖淑玉..Changes of serum thyroid hormone and plasma catecholamine of 16 th and 17 th Chinese Expeditioners in Antarctic environment[J].极地研究(英文版),2003,14(2):124-130,7.

基金项目

This work was support by Chinese National Science Foundation (No.3997801 ). (No.3997801 )

极地研究(英文版)

1674-9928

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