波谱学杂志2007，Vol.24Issue(2)：125-132,8.
3,5-二甲基金刚胺盐酸盐的NMR研究
An NMR Study on 3,5-Dimethyladamantanamine Hydrochloride Salt
摘要
Abstract
1H and 13C NMR spectroscopy was used to study the structure and configuration of 3,5-dimethyladamantanamine hydrochloride salt.Complete NMR assignments were made using DEPT.1H-1H COSY,HSQC and HMBC techniques.The NMR data indicated that the compound has a rigid structure and is comprised of two diastereomeric forms.There are ten peaks in the 13C NMR spectrum of the compound within the region δc 29～54 ppm.Because the compound has two different molecular configurations,there exist three peaks of quaternary carbons in the 13C NMR spectrum and two peaks of methyl groups in the 1H NMR spectrum.The two plane angles between the tertiary proton H5 and three adiacent CH2 are near 60,resulting in very small coupling constants among these protons.Consequently,the resonance of these protons can not be resolved and presents as a singlet in the 1H spectrum.关键词
NMR/归属/3,5-二甲基金刚胺盐酸盐/非对映体Key words
NMR,assignments,3,5-dimethyladamantanamine hydrochloride,diastereomeric forms分类
化学化工引用本文复制引用
任会学,林吉茂,孙友敏,常乃丰,王琦..3,5-二甲基金刚胺盐酸盐的NMR研究[J].波谱学杂志,2007,24(2):125-132,8.基金项目
This work was supported by the Shandong Province Outstanding. （）
