中国癌症防治杂志2009，Vol.1Issue(2)：130-133,4.
鼻咽癌调强放疗根据CT和MRI勾画腮腺的比较研究
Comparing the difference of contouring parotid based on CT and MRI in NPC patients treated with IMRT
摘要
Abstract
Objective To compare the differences of volume and DVH between the CT-defined and the MRI-defined parotids for intensity modulation radiated therapy (IMRT) planning on 20 patients with nasopharyngeal carcinoma (NPC).Methods Twenty patients diagnosed NPC from May 2008 to November 2008 were enrolled in this study.They received MRI and CT scan one week before radiotherapy and the images were transmitted to the treatment planning system,where the volume of parotid based on CT or MRI were contoured respectively.After fusing the CT/MRI image by using mutual information method,the difference of the volume between CT-defined and the MRI-defined parotid was evaluated.The IMRT plan was based on CT image,then the difference of DVH between CT-defined and MRI-defined parotid was compared.Results The mean volumes of parotid contoured on CT and on MRI were (24.53±1.96×7.23)cm3 and (31.75±1.96×12.05)cm3 respectively,the mean V30-CT and V30-MR were (39.29%±1.96×9.30)% and (47.73%±1.96×9.54)% respectively,and the mean D50-CT and D50MR were (2 716±1.96×220)cGy and (3 000±1.96×339)cGy respectively.Conclusion s The contoured volume based on MRI is more accurate than that based on CT.The main difference between them is at the deep leaf of the parotid,parotid duct and subparotid.Contouring the parotid based on CT image would miss some part of the parotid and would influence the accuracy of the V30 and D50 in some cases.关键词
腮腺/MR/CT/调强放疗/鼻咽癌Key words
Parotid/ MRI/CT/IMRT/Nasopharyngeal carcinoma分类
医药卫生引用本文复制引用
陈炬辉,吴海山,郑步宏,李奇欣,柏朋刚,吴君心..鼻咽癌调强放疗根据CT和MRI勾画腮腺的比较研究[J].中国癌症防治杂志,2009,1(2):130-133,4.基金项目
卫生部科学基金福建省卫生教育联合攻关计划项目(WKJ2008-2-47-1) （WKJ2008-2-47-1）
