中国现代医学杂志2004，Vol.14Issue(20)：13-15,3.
特发性肺纤维化患者支气管肺泡灌洗液细胞对肺功能的影响
Correlation between cells obtained by bronchoalveolar lavage and pulmonary function in idiopathic pulmonary fibrosis
温华 1宋玉 1康健 1李振华 1侯显明 1于润江1
作者信息
- 1. 中国医科大学附属第一医院,呼吸疾病研究所,辽宁,沈阳,110001
- 折叠
摘要
Abstract
Objective: The aim of this study was to investigate the role of cells in bronchoalveolar lavage fliud (BALF) samples on pulmonary function in patients with idiopathic pulmonary fibrosis (IPF). Methods: Thirty two patients with IPF underwent pulmonary function tests(PFTs) and fiberoptic bronchoscopy and bronchoalveolar lavage (BAL) at rest. HE stain was used for cell populations analysis. Results: There was a significant negative correlation between the percentage of eosinophils (Eos%) in BALF samples and % VC (r =-0.37, P ＜0.05) or %DLCO (r =-0.47,P ＜0.01), no such relationship was demonstrated for the percentage of any other cell type. An inverse relationship was found between V50% or V25% from pulmonary function and the percentage of neutrophils (Neu%) (r =-0.66, P ＜0.01; r =-0.45, P ＜0.05, respectively) in BALF samples. Conclusion: The results suggest that eosinophilic cells and neutrophilic cells may contribut to pulmonary dysfunction in patients with IPF.关键词
特发性肺纤维化/支气管肺泡灌洗液/细胞/肺功能试验Key words
idiopathic pulmonary fibrosis/bronchoalveolar lavage/cells/pulmonary function tests分类
医药卫生引用本文复制引用
温华,宋玉,康健,李振华,侯显明,于润江..特发性肺纤维化患者支气管肺泡灌洗液细胞对肺功能的影响[J].中国现代医学杂志,2004,14(20):13-15,3.
