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黑素转铁蛋白在家兔网织红细胞非转铁蛋白结合铁摄取中的作用

陈文芳 钱忠明

中国病理生理杂志2000,Vol.16Issue(12):1317-1319,3.
中国病理生理杂志2000,Vol.16Issue(12):1317-1319,3.

黑素转铁蛋白在家兔网织红细胞非转铁蛋白结合铁摄取中的作用

Role of P97 in non- transferrin bound iron uptake by rabbit reticulocytes

陈文芳 1钱忠明2

作者信息

  • 1. 青岛大学医学院生理教研室,山东青岛 266021
  • 2. 香港理工大学应用生物及化学技术系
  • 折叠

摘要

Abstract

AIM: To investigate the possible role of P97 in non - transferrin bound iron uptake by rabbit reticulocytes. METHODS: The iron uptake were measured by the method of radioisotope (5gFe). RESULTS: (1) Only PI - PLC treatment had no apparent effect on iron uptake by reticulocytes (P > 0.05); (2) Reticulocytes, pretreated by pronase and then by PI - PLC, give a significant decrease in iron uptake in cytosol and in hemne ( P < 0.01). CONCLUSION: The results support the possibility that P97 might be able to be expressed on the membrane of reticulocytes and plays a role in non - transferrin bound iron uptake by this type of cells in the rabbit.

关键词

转铁蛋白//网状细胞

Key words

Transferrin/Iron/Reticulocytes

分类

医药卫生

引用本文复制引用

陈文芳,钱忠明..黑素转铁蛋白在家兔网织红细胞非转铁蛋白结合铁摄取中的作用[J].中国病理生理杂志,2000,16(12):1317-1319,3.

中国病理生理杂志

OA北大核心CSCDCSTPCD

1000-4718

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