西北国防医学杂志2001,Vol.22Issue(2):135-136,2.
维持恒定SEF普鲁卡因对七氟醚呼末浓度的影响
The influence of intravenous procaine infusion to end-tidal sevoflurane concentration during hold constant SEF
摘要
Abstract
Objective:To examine the changes of end-tidal sevoflurane concentration to hold a constant EEG spectral edge frequence(SEF9-11 Hz) during continuous procaine infusion.Methods:Eight patients,ASA Ⅰ~Ⅱ,scheduled for no-thoracic operations were included.After intubation,end-tidal sevoflurane concentrations were regulated so that SEF was held between 9 and 11 Hz for at least 1 hour,then 1% procaine was infused intravenously at a rate of 1mg*kg-1*min-1.After continuous procaine infusion for 30 min,end-tidal sevoflurane concentrations were again regulaed so as to hold constant SEF between 9 and 11 Hz. Results:End-tidal sevoflurane concentrations to hold SEF between 9 and 11 Hz were 1.62%±0.04% before intravenous procaine infusion and were 1.32%±0.07%,reduced about 20%,after intravenous procaine infusion for 30 min.Conclusion:The inhibitive effect of procaine to brain is weak in clinical common doses.关键词
麻醉学/普鲁卡因/七氟醚呼末浓度分类
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耿智隆,张宏,靳冰..维持恒定SEF普鲁卡因对七氟醚呼末浓度的影响[J].西北国防医学杂志,2001,22(2):135-136,2.