西安医科大学学报2001，Vol.22Issue(2)：135-137,150,4.
复合人工骨修复股骨头骨缺损的影像学研究
A scintigraphic study of composited bone substitute in the repair of bone defect of femoral head
摘要
Abstract
Objective To evaluate the effect of bBMP-collagen-coral composited bone substitute in treatment of osteonecrosis of the femoral head(ONFH).Methods Canine bone defect of bilateral femoral head was established,They were devided into 4 groups:Ⅰ.composited bone substitute group(n=5),Ⅱ.muscle pedicle bone group (n=5),Ⅲ.simple coral group(n=4),Ⅳ.control group:contralateral hip(n=14).Roentgenography,Scintigraphy,MRI,CT were examined and studied at various time.Results ①Scintigraphic changes:In group Ⅰ,static bone image showed increased radionuclide uptake,but blood flow and blood-pool image didn't show in 6 and 12 week;②MRI:There was much more new bone formation in the bone defect of group Ⅰ;In group Ⅳ,there was fatty bone marrow which was surrounded with sclerotic bone;③Resules of roentgenographic and CT:In 14-16 weeks,in group Ⅰ,the coral was absorbed and most of the bone defects were closed completely;In the rest groups,part of each bone defect was remained except that in group Ⅳ,cystic sclerosis was formed.Conclusion The composited bone substitute possesses a superior osteoinductivity and osteoconductivity in the repair of bone defect of femoral head,but it can't improve the revascularization of ONFH.关键词
股骨头坏死/骨缺损/骨形态发生蛋白/人工骨/影像学分类
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同志勤,徐小良,王坤正,宋厂义..复合人工骨修复股骨头骨缺损的影像学研究[J].西安医科大学学报,2001,22(2):135-137,150,4.
