南华大学学报(医学版)2001，Vol.29Issue(2)：136-138,3.
芸香甙对体外冲击波碎石术时肾功能的保护作用
Protection of Renal Function from Damage Due to ESWL by Rutoside
陈仙 1龙炳衡 1王毅 1刘卓然 1彭荣章 1刘水清 1何岳清 1罗志刚1
作者信息
摘要
Abstract
Objective: In order to study the effects of rutoside (Ru) on renal damage induced by ESWL. Methods: 27 cases of renal stone undergone anaesthesia-free ESWL,were randomly assigned into 2 groups: the rutoside (Ru) group(n=15)and the control group (n=12). For the former group, rutoside was given orally for 3 succesive days,20 mg each time,3 times a day before ESWL,while the control group received no medication. Urinary albumin(ALB), immunoglobulin-G(IgG), β2 -microglobulin(β2 -MG) and Tamm-Horsfall protein(THP),and the serum level of superoside dismutas(SOD) and malonyldehyde(MDA) were determined before and after ESWL. Results: In the control group,a significant increase of urinary ALB、IgG、β2-MG and the serum level of MDA ,and a marked decrease of urinary THP and the serum level of SOD (P<0.01) were noted after ESWL .While there was a significant decrease of urinary ALB、IgG、β2-MG and the serum level of MDA, and a marked increase of urinary THP and the serum level of SOD(P<0.01) in the rutoside group compared with the control group. Conclusion: the results suggest that rutoside has protective effect on renal damage induced by ESWL.关键词
体外冲击波碎石术/肾功能/尿石症/芸香甙分类
医药卫生引用本文复制引用
陈仙,龙炳衡,王毅,刘卓然,彭荣章,刘水清,何岳清,罗志刚..芸香甙对体外冲击波碎石术时肾功能的保护作用[J].南华大学学报(医学版),2001,29(2):136-138,3.
