动物学研究2009，Vol.30Issue(2)：137-143,7.DOI:10.3724/SP.J.1141.2009.02137
文昌鱼一个GATA基因在胚胎发育中的表达图式
Developmental Expression of an Amphioxus (Branchiostoma belcheri) Gene Encoding a GATA Transcription Factor
摘要
Abstract
GATA factors are evolutionarily conserved and play crucial roles during embryonic development in both vertebrates and invertebrates. Vertebrate GATAs can be divided into two subgroups, the GATA1/2/3 and the GATA4/5/6 classes. Through genomic analysis, we have identified three GATA factors, representing the GATA1/2/3 and GATA4/5/6 subfamilies respectively, and one GATA like protein in the genome of the basal chordate amphioxus (Branchiostoma floridae, cephalochordata). Partial sequence of GATA123 in the amphioxus Branchiostoma belcheri (BbGATA123) was cloned and its expression pattern during early embryonic development was studied. Expression of BbGATA123 is first detected in the mesendoderm during gastrulation. Interestingly, in the late neurula and early larva stages, it is expressed strongly in the cerebral vesicle and the mid gut region. Its expression is compared to Otx, a gene known crucial for the development of anterior structures. Our observations suggest that GATA123, together with Otx, might play an important role in the development of amphioxus cerebral vesicle, the counterpart of the vertebrate brain.关键词
GATA因子/表达图式/文吕鱼/白氏文昌鱼Key words
GATA factors/Expression pattern/Amphioxus/Branchiostoma belcheri分类
生物科学引用本文复制引用
张煜,毛炳宇..文昌鱼一个GATA基因在胚胎发育中的表达图式[J].动物学研究,2009,30(2):137-143,7.基金项目
Supported by grants from the National Natural Science Foundation of China (30425011 （）
30530380) （）
国家杰出青年科学基金(30425011) （30425011）
国家自然科学基金重点项目(30530380) （30530380）
