中国临床康复2002,Vol.6Issue(9):1384-1384,1.
小儿精神发育迟滞合并癫痫的治疗
Improvement of mental retardation plus epilepsy in children following management
刘振寰 1潘佩光1
作者信息
- 1. Nanhai City Hospital for Women and Children,Nanhai,528200,China
- 折叠
摘要
Abstract
Objective To investigate the effective management approaches for mental retardation plus epilepsy in children.Method Sodium valproat[15~ 60 mg/( kg· day)] or nitrazepam[0.5~ 1 mg/( kg· day) ] and guanmaishu containing hyoscyamine(0.0045~ 0.045 mg/( kg· day)] as adjuvant were administered for 1.5~2 consecutive years.EEG,three dimensional Doppler ultrasonic examination of cerebral vessels were performed.Result Favorable therapeutic effect was obtained in 25 cases(48.1% ),good effect in 12 cases(23.1% ).Conclusion Favorable therapeutic effect of hyoscyamine in epilepsy is correlated with improved cerebral microcirculation,cortical choline receptor blocking ,reduced conduction between synapses.These factors all inhibit onset of epilepsy.关键词
mental retardation/epilepsy/management/hyoscyamine/microciculationKey words
mental retardation/epilepsy/management/hyoscyamine/microciculation分类
医药卫生引用本文复制引用
刘振寰,潘佩光..小儿精神发育迟滞合并癫痫的治疗[J].中国临床康复,2002,6(9):1384-1384,1.