中国临床康复2004，Vol.8Issue(7)：1384-1385,2.
电针损伤大鼠中脑后神经元结构和功能的变化
Structural and functional changes of midbrain neurons in rats injured by electroacupuncture
林野 1万虹 2历俊华 2翟晶2
作者信息
- 1. 吉林大学中日联谊医院骨科,吉林省长春市,130021
- 2. 北京市神经外科研究所,北京市,100050
- 折叠
摘要
Abstract
BACKGROUND:The function of neurons is closely relative with the health of human bodies.Presently,many methods have been used to detect the structural and functional changes of neuronal axons.But studies on dendrite are very limited. OBJECTIVE:To detect the changes of microtubule-associated protein-2(MAP2) immunoreaction in the midbrain of rats injured by electroacupunture. DESIGN:A case-control animal experiment. SETTING and MATERIALS:The experiment was made in the Medical Research Center,China-Japan Union Hospital of Jilin University.Wistar rats,male or female, weighing(180± 120) g were subjected in the experiments.Each group included 6 rats. INTERVENTION:Brain tissues were taken out at different time to detect the changes of MAP2 immunoreaction, ollowing the midbrains of rat were injured with electroacupuncture. MAIN OUTCOME MEASURES:The changes of neuronal MAP2 immunoreaction and pathological changes at different time. RESULTS:Normal neuronal MAP2 staining was located mainly in the cytoplasm and dendrites.But after the injury of electroacupuncture,MAP2 immunoreactions were detected in different neurons: pycnosis neurons,gently injured neurons and normal neurons. CONCLUSION:MAP2 immunoreaction is a good marker to detect the function of neurons in the study of central nervous system injury.关键词
脑损伤/免疫学/树突/微管相关蛋白类分类
医药卫生引用本文复制引用
林野,万虹,历俊华,翟晶..电针损伤大鼠中脑后神经元结构和功能的变化[J].中国临床康复,2004,8(7):1384-1385,2.
