中国临床康复2004，Vol.8Issue(7)：1392-1393,2.
肌酸磷酸激酶增高的脊髓性肌萎缩症10例临床与肌电图分析
Clinical and electromyographical study on 10 cases of spinal muscular atrophy associated by elevated plasma creatine kinase
刘英 1高国勋1
作者信息
- 1. 四川省人民医院神经内科,四川省成都市,610072
- 折叠
摘要
Abstract
AIM:To study the relationship between electromyography(EMG) diagnoses and clinical presentations in spinal muscular atrophy(SMA) associated with elevated plasma creatine kinase(CK). METHODS:Clinical evaluation and EMG were performed on 10 patients with SMA associated with elevated CK.Muscle biopsy was taken from 6 of the 10 cases. RESULTS:Elevated CK at different level was detected in various type of SMA. EMG showed that 8 cases were neurogenic SMA,and 2 cases were mixed injury.Histomorphological examination demonstrated 1 case of myogenic atrophy and 5 cases of neurogenic atrophy. CONCLUSION:Elevated CK cannot be used as the diagnostic marker for differentiating SMA from progressive muscular dystrophy.Diagnosis should be made after examinations of CK,EMG and muscle biopsy.Repeated EMG results are more reliable for a diagnosis of myogenic atrophy.Biopsy results can provide reliable evidences for diagnosis when EMG is not typical.关键词
脊髓性肌萎缩/肌酸磷酸激酶/肌电图分类
医药卫生引用本文复制引用
刘英,高国勋..肌酸磷酸激酶增高的脊髓性肌萎缩症10例临床与肌电图分析[J].中国临床康复,2004,8(7):1392-1393,2.
