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现场诊断日本血吸虫感染常用方法比较

余金明 袁鸿昌

同济大学学报(医学版)2001,Vol.22Issue(1):1-4,4.
同济大学学报(医学版)2001,Vol.22Issue(1):1-4,4.

现场诊断日本血吸虫感染常用方法比较

Comparison of Common Methods in the Field Diagnosis of Schistosoma Japonicum Infection

余金明 1袁鸿昌2

作者信息

  • 1. 同济大学医学院预防医学教研室,
  • 2. 复旦大学医学院流行病学教研室,
  • 折叠

摘要

Abstract

Objective Comparing the performances of the three diagnostic techniques in the most important endemic areas for schistosomiasis japonica in China.Methods The Kato-Katz technique, hatching test and indirect hemagglutination assay (IHA) were used to detect schistosoma japonicum infection in two villages, Zhonjiang and Zhuxi, which were selected from Hubei Province and Jiangxi Province, respectively. Single Kato examination was conducted in Zhonjiang Village, 7 repeated Kato examinations were conducted in Zhuxi Village. Basis epidemiologic data were collected in the same time.Results In both village, the trends of prevalences with age and sex were the same with the different methods and the proportion of positives detected by IHA and hatching increased with intensity of infection. The results of 7 repeated Kato examinations and hatching were used as gold standard (Zhuxi). Using this gold standard in Zhuxi, the sensitivity of IHA was 80% and its specificity 48%. The sensitivity of a single Kato measurement was 68% and of hatching 33%. In Zhonjiang, however, proportions of positives were considerably higher for hatching than for a single Kato examination.Conclusion The Kato-Katz technique is recommended as the method of choice for the field diagnosis of schistosoma japonicum infection. Hatching is much more tedious, provides inconsistent and only qualitative results, and is not more sensitive than a single Kato. IHA is more sensitive but it results in many false positive cases and is therefore only suitable as an auxiliary method.

关键词

血吸虫,日本/诊断/改良加藤法/孵化法/间凝法

分类

医药卫生

引用本文复制引用

余金明,袁鸿昌..现场诊断日本血吸虫感染常用方法比较[J].同济大学学报(医学版),2001,22(1):1-4,4.

同济大学学报(医学版)

1008-0392

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