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Differential Expressing of Centromere Protein CenpG in Breast Cancer

高技术通讯(英文版)2002,Vol.8Issue(1):1-4,4.
高技术通讯(英文版)2002,Vol.8Issue(1):1-4,4.

Differential Expressing of Centromere Protein CenpG in Breast Cancer

Differential Expressing of Centromere Protein CenpG in Breast Cancer

1

作者信息

  • 1. College of Life Sciences, Beijing Normal University, Beijing 100875, P.R.China;Dongzhimen Hospital of Beijing University of Chinese Traditional Medicine, Beijing 100700, P.R.China;Tayuan Hospital of Beijing Red Cross, Beijing, 100083, China., Zhang Huanxiang, ;College of Life Sciences, Beijing Normal University, Beijing 100875, P.R.China;College of Life Sciences, Beijing Normal University, Beijing 100875, P.R.China;College of Life Sciences, Beijing Normal University, Beijing 100875, P.R.China
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摘要

Abstract

Using indirect immunofluorescence (IIF), an anti-centromere protein CenpG-serum was verified. Western blot of the protein extracts of 31 samples of breast cancer tissues and their normal (not cancerous ) tissues a little far away from them in the same individuals showed that, in the majority of the tests (71%), centromere protein CenpG over expressed in breast cancer tissues. And moreover, a kind of protein component whose molecular weight is 43 kd, and which can be recognized by anti-CenpG serum was found in two of the cancer samples. The results suggested that CenpG (together whith it, there may be other relative components),which has been found and named recently, may be related to cancer,and its differential expressing is probably related to malignant cell proliferation.

关键词

Breast cancer/Centromere protein/Cenp

Key words

Breast cancer/Centromere protein/Cenp

分类

医药卫生

引用本文复制引用

..Differential Expressing of Centromere Protein CenpG in Breast Cancer[J].高技术通讯(英文版),2002,8(1):1-4,4.

基金项目

This work was supported by the funds of State Major Basic Research Development Project (“97.3" Project) of China (No. G1999053901) and the National Natural Science Foundation of China(No. 39430080 and 39970361). (“97.3" Project)

高技术通讯(英文版)

OAEI

1006-6748

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