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256例药物性肝病血清酶谱学变化特点及预后分析

刘序友 李庭华 杨继雄 邱粤勇

中国现代医生2009,Vol.47Issue(17):14-15,28,3.
中国现代医生2009,Vol.47Issue(17):14-15,28,3.

256例药物性肝病血清酶谱学变化特点及预后分析

Change Feature of Blood Serum Zymogram and Prognostic Analysis of 256 Cases of Drug-induced Liver Injury

刘序友 1李庭华 1杨继雄 1邱粤勇1

作者信息

  • 1. 广东省惠东县人民医院肝病科,广东,惠东,516300
  • 折叠

摘要

Abstract

Objective To analyze the etiology and clinical features of drug-induced liver damage,in order to draw more attention to this problem. Methods Two hundred and fifty-six cases over a 10-year period were retrospectively analyzed. Results A variety of drugs,in-cluding traditional Chinese medicines(23.8% of our total cases)and immunosuppressive agent(11.7%)caused liver damage. The main clinical manifestations of it were fatigue,nausea,vomiting and jaundice. In 78.5% of our cases,the symptoms were relieved or completely disappeared, but there was still 6.6% mortality rate. Conclusion The clinical features of drug-induced liver damage are of no specificity,and the mortality of it is high. Liver function should he monitored when suspected are prescribed.

关键词

药物性肝病/血清酶谱/预后分析

Key words

Drug-induced liver disease/Blood serum zymogram/Prognostic marker

分类

医药卫生

引用本文复制引用

刘序友,李庭华,杨继雄,邱粤勇..256例药物性肝病血清酶谱学变化特点及预后分析[J].中国现代医生,2009,47(17):14-15,28,3.

中国现代医生

1673-9701

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