昆明医学院学报2001，Vol.22Issue(1)：14-16,3.
1-乙酰基佛司可林对兔及人眼内压的影响
Effects of 1-acetylforskolin on Intraocular
Pressure in Rabbits and Men
1
作者信息
- 1. 昆明医学院;昆明医学院;昆明医学院;昆明制药股份有限公司质量部,;昆明医学院第二附属医院眼科;中国科学院昆明植物研究所植化室;Kunming Institute of Botan y,
- 折叠
摘要
Abstract
To investigate effects of l% l-acetylforskoin (l-aF) suspension eye-drops administeredtopically on intraocular pressure (IOP) in rabbits and men, and observe the loca l irritation of the drug． l% l-aF suspension eye-drops was prepared and was instilled into one of e yes while the corresponding vehicle into the contralateral eye as control． IOP was measured b y pneumatonometer before and after administration． l%1-aF suspension eye-drops s ig nificantly reduced IOP in rabbits reaching the maximum reduction of 2.2 mmHg and lasting a t least 3 hours． But it didnt show significant effects in men． There was little local irritati on neither in rabbits nor in men． l% l-aF suspension eye-drops significantly reduced IOP in normal rabbit s, but not in men． No local irritation was observed in rabbits and in men．关键词
1-乙酰基佛司可林/眼内压/兔/人分类
医药卫生引用本文复制引用
..1-乙酰基佛司可林对兔及人眼内压的影响[J].昆明医学院学报,2001,22(1):14-16,3.
