国际眼科杂志2003，Vol.3Issue(4)：14-17,4.
高浓度糖对体外培养的视网膜Müller细胞膜离子通道的影响
Effects of high concentration glucose on ion channel of retinal Müller cells cultured in vitro
摘要
Abstract
Aim To observe the effects of high concentration glucose on the calcium-dependent-potassium channel of rabbits' retinal identified by immunohistochemical staining and transmission electron microscopy. Patch-clamp technique was used to observe the change in the calcium-dependent-potassium channel in retinal Müller cells caused by high concentration glucose at different periods. Results High concentration glucose eould inhibit the calcium-dependent-potassium channel of cultured retinal Muller cells in a time-dependent manner. Conclusion High concentration glucose may reduce the biological functions of Müller cells by inhibiting calcium-dependent-potassium channel.关键词
高浓度葡萄糖/钙依赖性钾通道/Müller细胞Key words
high glucose concentration/calcium-dependent-potassium channel/Müller cells分类
医药卫生引用本文复制引用
宋鄂,张岩,王秋丽,杜宝东,王越辉,扬威,张文杰..高浓度糖对体外培养的视网膜Müller细胞膜离子通道的影响[J].国际眼科杂志,2003,3(4):14-17,4.基金项目
青年教师及临床新疗法和医学技术基金会资助(项目编号:20030111 （）
200109) （）
