中国现代医学杂志2005，Vol.15Issue(10)：1461-1464,1468,5.
丁丙诺啡、曲马多用于雷米芬太尼全麻苏醒过渡期镇痛
Analgesic effect of buprenorphine comparied with tramadol on emergence after remifentanil-based general anesthesia
杨金凤 1常业恬 1周志国2
作者信息
- 1. 中南大学湘雅二医院,麻醉科,湖南,长沙,410005
- 2. 湖南省肿瘤医院,麻醉科,湖南,长沙,410013
- 折叠
摘要
Abstract
[Objective] To observe the analgesic effect of buprenorphine comparied with tramadol on emergence.after remifentanil-based general anesthesia. [Methods] 120 patients undergoing elective thoracotomy under general anesthesia were randomly divided into 3 equal groups(group A, B, C), stoped general anesthesia when starting to shut off thorax and injected buprenorphine 3 μg/kg at group A, tramadol 2 mg/kg at group B, 0.9%NS 2 mL at group C.At three groups the HR, MAP, SPO2, PETCO2, RS, RSS at every time point(t1～t6) and BCS, the waken time, PCA bolus times, PCA dosage, side reactions were observed. [Results] There were more steadily hemodynamics at group A、B than group C; Since 10' after drugs given RS of group A、B were apparently lower than group C (P ＜0.01).Since 30' after drugs given RSS of group A、B were obviously higher than group C (P ＜0.01), and there were statistically significant difference (Avs B P ＜0.01 ) since extubation; There were statistically significant difference of BCS (A, B vs C P ＜0.01 ); Sweating at group B were obviously higher than group A or C (P＜0.05); There were statistically significant difference about PCA bolus times and PCA dosage among three groups (C＞B＞A, P ＜0.01 or P ＜0.05). [Conclusion] Buprenorphine and tramadol can safely and effectively analgesia on the emergence after remifentanil-based general anesthesia, moreover buprenorphine has better effect and less side reactions关键词
丁丙诺啡/曲马多/雷米芬太尼/全麻/镇痛Key words
buprenorphine/tramadol/remifentanil/general anesthesia/analgesia分类
医药卫生引用本文复制引用
杨金凤,常业恬,周志国..丁丙诺啡、曲马多用于雷米芬太尼全麻苏醒过渡期镇痛[J].中国现代医学杂志,2005,15(10):1461-1464,1468,5.
