中国骨伤2001，Vol.14Issue(3)：148-149,2.
生骨再造散对激素性股骨头坏死家兔血脂的影响
Effects of Shengguzaizao San on blood-lipid of hormone-induced femoral head necrosis in rabbits
张晓刚 1王钢 1邓沂 1刘建军 1邱桐 1任远2
作者信息
- 1. 甘肃中医学院附属医院,
- 2. 甘肃中医学院中药系,
- 折叠
摘要
Abstract
Objective To explore the effects of Shengguzaizao San(SGZZS)(a prescription of traditional Chinese medicine on blood-lipid in models of hormoneinduced femoral head necrosis in rabbits.Methods 45 rabbits were divided into 5 groups randomly:1.control group;2.model group;3.SGZZS(Chinese herbs)group;4.SGZZS and operation group and 5.Mashibugu Pian(MSBGP)(Chinese herb)group.Hormoneinduced femoral head necrosis models were produced by glucocorticoid hormone.From the 6th week after production of models,SGZZS was given to the rabbits of 3 and 4 groups(3.2g*kg-1*d-1),MSBGP given to 5 group(3.2g*kg-1*d-1)and the same capacity of normal saline to 1 and 2 groups.The contents of cholesterol,triglycerido and high density lipoprotein(HDL)of the rabbits were determined at 5th weeks after the models were made and 5th weeks after the drugs were given.Results Compared with control group,the contents of cholesterol and triglycerido in model group increased obviously,but the content of HDL decreased obviously.Compared with model group,the contents of cholesterol and triglycerido in the three treatment groups decreased obviously,but the content of HDL increased obviously.There were no marked difference between the two SGZZS groups and MSBGP group.Conclusion The mechanism of SGZZS for the treatment of femoral head necrosis is seemingly related to its effects on blood-lipid.关键词
中草药股骨头坏死血脂分类
医药卫生引用本文复制引用
张晓刚,王钢,邓沂,刘建军,邱桐,任远..生骨再造散对激素性股骨头坏死家兔血脂的影响[J].中国骨伤,2001,14(3):148-149,2.
