液晶与显示2007，Vol.22Issue(1)：1-5,5.
特性炔类液晶的简便合成
Convenient Preparations of Acetylene Liquid Crystal Compounds with Special Characters
摘要
Abstract
4,4'-dialkyl-4-ethynylbicyclohexyl (1) and their coupled derivatives 1,4-bis ( ( 4,4'-dialkyl-bicyclohex)-4-yl) butadiyne (2), 1,4-bis ( 2-( ( 4,4'-dialkyl-bicyclohex)-4 yl ) ethynyl )arene(3) are very important liquid crystal compounds with some special characters. In this paper, the preparations of these compounds were developed in which 4,4'-dialkylbicyclohexyl-4-carbonitrile(4) is used as the starting material. Firstly, key intermediate 4-aceto-4,4'-dial-kyl-bicyclohexyl (5) was synthesized in good yield through the addition of methyl lithium to compound 4 followed by hydrolyzation, Then, the compound 1 was prepared in excellent yield through the reaction of compound 5 with Grignard reagent whose presumed mechanism was proposed. Acetylene compound 2 was synthesized through the oxidative self-coupling of compound 1, and the preparation of acetylene compound 3 was advanced through the coupling of compound 1 with aryldibromide in the Pd(0) catalyst system. These preparations have high yields and short procedure which are high efficient synthesis methods, and the preparation method of compound 1 is never reported in any literatures heretofore.关键词
1,4-双(2-((4,4'-二烷基联环己)-4-基)乙炔基)芳烃/4,4'-二烷基-4-乙炔基联环己烷/1,4- 双((4,4'-二烷基联环己)-4-基)丁二炔/4-乙酰基-4,4'-二烷基-联环己烷/格氏试剂/空阻 炔/氧化偶联/二溴代芳烃Key words
1,4-bis( 2-( ( 4,4'-dialkyl-bicyclohex)-4-yl ) ethynyl) arene/4,4'-dialkyl-4-ethynyl-bicyclohexyl/1, 4-bis (( 4, 4'-dialkyl-bicyclohex)-4-yl) butadiyne/4-aceto-4, 4'-dialkylbicyclohexyl/Grignard reagent/hindered acetylene/oxidative coupling/aryldibr分类
信息技术与安全科学引用本文复制引用
李韶辉,刘红伟,刘鑫勤,郭章红,史子谦..特性炔类液晶的简便合成[J].液晶与显示,2007,22(1):1-5,5.基金项目
Foundation item: Sponsored by National "863" Project(No.003AA311090) （No.003AA311090）
