天津工业大学学报2001，Vol.20Issue(1)：1-5,5.
壳聚糖膜的制备及其对人、大鼠皮肤成纤维细胞的相容性
Fabrication of chitosan films and their biocompatibility to human neofetus dermal and rat dermal fibroblasts
马建标 1王红军 2何炳林 2陈家童3
作者信息
- 1. 天津工业大学,
- 2. 南开大学高分子化学研究所,
- 3. 南开大学分子生物学研究所,
- 折叠
摘要
Abstract
Some chitosan films were fabricated by casting method using glycerol as plasticity agent in dilute acetic acid solution and then characterized.Rat dermal fibrobalasts and human neofetus dermal fibroblasts were cultured in vitro to evaluate the biocompatibility of the chitosan films.The results showed that some cells cold be broken at early stage of the culture because there were too many basic amino groups in chitosan which would tightly bind the negative surface of cells.However,while the culture was continued,cells could normally grow and proliferated.It was found that new cells would be inhibited by contact to each other after they were spread all over the surface of the films.In addition,it was also observed that human neofetus dermal fibroblasts grew slower than rat dermal fibroblasts.关键词
壳聚糖膜/大鼠皮肤成纤维细胞/人胎儿皮肤成纤维细胞/细胞培养分类
化学化工引用本文复制引用
马建标,王红军,何炳林,陈家童..壳聚糖膜的制备及其对人、大鼠皮肤成纤维细胞的相容性[J].天津工业大学学报,2001,20(1):1-5,5.
