短瓣金莲花中一个新的黄酮炭苷化合物OACSCDCSTPCD
Acylated Flavone C-glycosides from Trollius ledebouri Reichb
一个新的酰化黄酮炭苷化合物(1)和9个已知的黄酮炭苷从短瓣金莲花中分离得到,化合物1的结构通过HRMS、IR、1H、13C NMR、HMQC、HMBC等光谱学方法鉴定为7-甲氧基-2″-O-(2-甲基丁酰基)荭草苷.并以耳肿胀法评价所得黄酮化合物的抗炎活性.
A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with nine known C-glycosyflavones (2-10).The structures were elucidated by spectroscopic methods,including HRMS,IR,1H and 13C NMR and 2D experiments (COSY,HMQC and HMBC).The anti-inflammatory activities of C-glycosyflavones were tested on TPA-induced mice ear edema (in vivo).
吴新安;赵毅民;朱捷;吴静;朱素琴;徐国胜
105医院药械科,合肥,230031北京军事医学科学院毒物药物研究所,北京100850105医院药械科,合肥,230031105医院药械科,合肥,230031105医院药械科,合肥,230031105医院药械科,合肥,230031
农业科技
短瓣金莲花黄酮炭苷抗炎
Trollius ledebouri ReichbC-glycosylflavoneanti-inflammation
《天然产物研究与开发》 2009 (1)
1-5,5
Foundation Item:The project was supported by the 11th Five-year Plant Fund of Nanjing Military Region (06MA54).
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