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前列腺癌的神经内分泌分化

Jingwen Wang Yang Yao

中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(3):150-153,4.
中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(3):150-153,4.

前列腺癌的神经内分泌分化

Neuroendocrine differentiation in prostate cancer

Jingwen Wang 1Yang Yao1

作者信息

  • 1. Department of Oncology, Shanghai Sixth People's Hospital, Jiaotong University, Shanghai 200233, China
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摘要

Abstract

Hormonal therapy is an important treatment for advanced/metastatic prostate cancer. But it can induce neuroen-docrine (NE) differentiation in prostate cancer cells. These NE cells will secrete manifold neural peptide or hormones which can lead to androgen-independent growth of non-NE tumor cells. When this happens, hormonal therapy becomes useless and indicates bad prognosis. In this paper, the mechanism of neuroendocrine differentiation and its relationship with androgen-independent were reviewed.

关键词

prostate cancer/ neuroendocrine differentiation/ drug resistance

Key words

prostate cancer/ neuroendocrine differentiation/ drug resistance

分类

临床医学

引用本文复制引用

Jingwen Wang,Yang Yao..前列腺癌的神经内分泌分化[J].中德临床肿瘤学杂志(英文版),2008,7(3):150-153,4.

中德临床肿瘤学杂志(英文版)

OACSTPCD

2095-9621

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