中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(3):150-153,4.
前列腺癌的神经内分泌分化
Neuroendocrine differentiation in prostate cancer
Jingwen Wang 1Yang Yao1
作者信息
- 1. Department of Oncology, Shanghai Sixth People's Hospital, Jiaotong University, Shanghai 200233, China
- 折叠
摘要
Abstract
Hormonal therapy is an important treatment for advanced/metastatic prostate cancer. But it can induce neuroen-docrine (NE) differentiation in prostate cancer cells. These NE cells will secrete manifold neural peptide or hormones which can lead to androgen-independent growth of non-NE tumor cells. When this happens, hormonal therapy becomes useless and indicates bad prognosis. In this paper, the mechanism of neuroendocrine differentiation and its relationship with androgen-independent were reviewed.关键词
prostate cancer/ neuroendocrine differentiation/ drug resistanceKey words
prostate cancer/ neuroendocrine differentiation/ drug resistance分类
临床医学引用本文复制引用
Jingwen Wang,Yang Yao..前列腺癌的神经内分泌分化[J].中德临床肿瘤学杂志(英文版),2008,7(3):150-153,4.