中国当代医药2009,Vol.16Issue(12):15-17,3.
ICU内呼吸机相关性肺炎的病原菌及耐药性分析
Analysis for the pathogens and drug resistance of VAP in ICU
华玮 1俞斌 1戴晓勇 1郑鹏翔1
作者信息
- 1. 上海市杨浦区中心医院急诊科,上海,200090
- 折叠
摘要
Abstract
Objective: To analyze the pathogens and the drug-resistance of ventilator-associated pneumonia (VAP) in ICU. Methods: Among 63 patients with VAP in intensive care unit (ICU) in our hospital between Jan 2007 and Dec 2008, pathogens distribution and drug-resistance rate were analyzed. Results: Totally 138 pathogens were cultivated altogether in all 63 VAP patients. Among the pathogens, the Gram-negative bacteria(GNB)accounted for 67.4%, the Gram-positive bac-teria(GPB) for 12.3%, and the fungi for 20.3%. Most of the GNB showed high resistance rote to common used antibiotics. Staphylococns anrens had severe drug-resistance to oxacillin but it was still highly susceptible to vancomycin and linezoid. Conclusion: GNB is still the major pathogens of VAP. Multi--drug--resistance (MDR) could be occurred in most of the pathogens. Given the possible multiple drug resistance of pathogen, appropriate antibiotics with low drug resistance of potential should be empirically used against infection. Pathogen test prior to or concurrent with anti-microbiological therapy is important in guiding the reasonable application of antibiotics.关键词
呼吸机相关性肺炎/病原菌/耐药性Key words
Ventilator-associated pneumonia(YAP)/Pathogen/Drug-resistance分类
医药卫生引用本文复制引用
华玮,俞斌,戴晓勇,郑鹏翔..ICU内呼吸机相关性肺炎的病原菌及耐药性分析[J].中国当代医药,2009,16(12):15-17,3.