国际医药卫生导报2009，Vol.15Issue(16)：15-18,4.DOI:10.3760/cma.j.issn.1007-1245.2009.16.005
广东新兴地区致病性A组链球菌病种分布及耐药性分析
Pathogenic group A streptococcus distribution of diseases and drug resistance analysis in Xinxing Guangdong province
摘要
Abstract
Objective To investigate clinical diseases distribution and drug re-sistance of the pathogenicity of group A Streptococcus (GAS) from Xinxing area in Guangdong and guide the clinical use.Methods 85 GAS isolates were collected from 2063 cases of school-age children's throat swab,pus and other specimens in Xinxing area during January 2007 to June 2009.Drug sensitivity tests were evaluated by the K-B disk diffusion method containing 5% fiber blood to the M-H agar.Resusts Pathogenicity of 85 GAS acute pharyngitis 36,suppurative tonsillitis 25,acute rheumatic fever 5,acute glomerulonephritis 6,psoriasis 4,Other diseases 9.The resistance rates to erythromycin and other macrolides was more than 77.65 percent,Except Clindamycin,GAS resistant to other antibiotics compared with the macrolides (P＜0.05),There was significant difference.Acute rheumatic fever and suppurative tonsillitis,acute pharyngitis cases of GAS resistant to the cephalosporins rate (P＜0.05),There was significant difference.Conclusions GAS pathogenicity is wider distribution in this area,Penicillins and cephalosporins should still be the first choice for the treatment or prevention of GAS infection.关键词
A组链球菌/病种分布/耐药性Key words
Group A Streptococcus/Distribution of disease/Drug resistance分类
医药卫生引用本文复制引用
黎国强,李云,谭志伟,欧国生..广东新兴地区致病性A组链球菌病种分布及耐药性分析[J].国际医药卫生导报,2009,15(16):15-18,4.基金项目
广东省医学科研基金立项(A2007684) （A2007684）
