高技术通讯2001，Vol.11Issue(3)：15-18,4.
鲈鱼口服生物胶囊疫苗的研究
Oral vaccination of Seaperch (Lateolabrax japonicus), Against
Vibrio ang uillarum Using Bioencapsulated Vaccine
摘要
Abstract
Challenge tests to sea perch fries challenged by the virulent strain of Vibrio a nguillarum (W-1) initially isolated from diseased sea perch (Lateolabrax ja ponic us) were investigated. The fries were seriously infected by the means of bacte ri al bath, bacterial bath after injury, injecting by muscle, their LD50 were 2.75 ×107cfu/ml, 4.68×106cfu/ml and 3.72×105cfu/fish, respectively. Then, th e heal th sea perch fry were orally vaccinated for 5days consecutively using two vacci ne s by the means of adding directly into food or bioencapsulation of Artemia naupl ii. The two vaccines, one is the microcapsulated vaccine (MC), the other is whol e cell bacterin (WC). The results showed the cumulative mortality of all 4 vacci ne groups were rather lower than those of control groups. The group of Artemia n auplii carrying microcapsulated vaccine had the highest relative percentage surv ival (RPS) in the all 4 vaccine-groups after a challenge test by injecting viab l e W-1 a week later, was 73.7%, the group of microcapsulated vaccine by adding di rectly into food was the second, its RPS was 56.8%. The rest two whole cell bact erin groups, one was directly adding into food, the other was carried by Artemia nauplii, their RPS were 52.6%, 36.8% respectively.关键词
鲈鱼/鳗弧菌/口服疫苗/生物胶囊/卤虫分类
生物科学引用本文复制引用
余俊红,纪伟尚,徐怀恕..鲈鱼口服生物胶囊疫苗的研究[J].高技术通讯,2001,11(3):15-18,4.
