Effect of Rapamycin on TGF-β1-induced epithelial-mesenchymal transition in LoVo colonic adenocarcinoma cellsOA
Effect of Rapamycin on TGF-β1-induced epithelial-mesenchymal transition in LoVo colonic adenocarcinoma cells
Objective:To investigate the effect of Rapamycin on epithelial-mesenchyrnal transition(EMT) of LoVo colonic adenocarcinoma cells in vitro.Methods:Cultured LoVo colonic adenocarcinoma cells were divided into three groups: n…查看全部>>
Objective:To investigate the effect of Rapamycin on epithelial-mesenchyrnal transition(EMT) of LoVo colonic adenocarcinoma cells in vitro.Methods:Cultured LoVo colonic adenocarcinoma cells were divided into three groups: negative control group,EMT-inducing group(TGF-β1) and EMT-interfering group(TGF-β1 plus Rapamycin).E-cadherin expression in LoVo cells was detected by Western Blot,while the expression of vimentin was evaluated through immunocytochemis…查看全部>>
Renhu Sun;Jiang Li;Jing Cui;Qing Lv;Xinghua Liu;Guobin Wang
Department of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, ChinaDepartment of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, ChinaDepartment of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, ChinaDepartment of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, ChinaDepartment of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, ChinaDepartment of general Surgery, Union Hospital, Tong ji Medical College,Huazhong Universty of Science and Technology, Wuhan 430022, China
临床医学
epithelial-mesenchymal transition(EMT)RapamycinTGF-β1Snail
epithelial-mesenchymal transition(EMT)RapamycinTGF-β1Snail
《南京医科大学学报(英文版)》 2009 (1)
炎性细胞因子在胃黏膜肠上皮化生中的作用及其机制研究
15-19,5
This work was supported by National Natural science foundation of China(No. 30772128).
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