眼科学报2003，Vol.19Issue(1)：15-19,5.
Scotopic Sensitivity of Central Retina in Early Age-Related Macular Degeneration
Scotopic Sensitivity of Central Retina in Early Age-Related Macular Degeneration
Changzheng Chen 1Lezheng Wu 1Futian Jiang 1Jiongji Liang 1De-Zheng Wu1
作者信息
- 1. Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
- 折叠
摘要
Abstract
Purpose: To test scotopic sensitivity and investigate whether there is rod systemdysfunction in the central retina in early age - related macular degeneration (AMD).Methods:Scotopic (450 nm stimulus) and photopic (white light stimulus) sensitivity in24 patients with early AMD was measured at 81 loci in central 25° of retina, andcompared with the age - match normal controls.Results: Mean scotopic sensitivity of AMD patients was significantly lower than that ofthe normal controls. The patients of reduced scotopic sensitivity were more than those ofreduced photopic sensitivity. Scotopic sensitivity deficit decreased with increasingeccentricity with the greatest deficit was 2. 5°to 5.0°.Conclusions: Scotopic sensitivity was decreased in the early stage of AMD. Theparafoveal rod cells were selectively damaged in AMD. Scotopic sensitivity testing inmacula may be a useful tool to diagnose and measure the fundus dysfunction of AMD.关键词
age-related macular degeneration/perimetry/rodKey words
age-related macular degeneration/perimetry/rod分类
医药卫生引用本文复制引用
Changzheng Chen,Lezheng Wu,Futian Jiang,Jiongji Liang,De-Zheng Wu..Scotopic Sensitivity of Central Retina in Early Age-Related Macular Degeneration[J].眼科学报,2003,19(1):15-19,5.
