中国临床康复2003，Vol.7Issue(10)：1519-1520,2.
不同剂量照射后猪垂体和靶腺器官的放射损伤
The irradiative injury in porcine pituitary and target organs after different single dose irradiation
乔广宇 1王迎选 2周定标 1汪力2
作者信息
- 1. 解放军总医院,神经外科,北京市,100853
- 2. 解放军总医院,放疗科,北京市,100853
- 折叠
摘要
Abstract
Aim To research the radiation response of the pituitary to the single dose irradiation.Method The porcine hypophysis was irradiated by 5,10,15 and 20 Gy single doses respectively.40 weeks after irradiation,all animals were exsanguinated and killed for pathologically examining the pituitary and the pituitary target organs.Results The percentage and the restorative degree of secretive function of the Leydig cell were lower in the irradiated groups than that in the control group,and they showed a negative correlation with the dose.The thyroid tissue showed obvious hyperplasia after the 10 Gy irradiation,but degeneration in the 15 and 20 Gy groups.No obvious changes were found about the adrenal tissue and pituitary under the light microscope after irradiation.Conclusion The pituitary is well - tolerant to the single 20 Gy irradiation,but it's hormone - producing cells and has the different radiative sensitivity. 关键词
立体定位技术/垂体/猪Key words
stereotaxic techniques/pituitary gland/swine分类
医药卫生引用本文复制引用
乔广宇,王迎选,周定标,汪力..不同剂量照射后猪垂体和靶腺器官的放射损伤[J].中国临床康复,2003,7(10):1519-1520,2.
