老年心脏病学杂志（英文版）2008，Vol.5Issue(1)：15-20,6.
Elevated serum uric acid level as a predictor for cardiovascular and all-cause mortality in Chinese patients with high cardiovascular risk
Elevated serum uric acid level as a predictor for cardiovascular and all-cause mortality in Chinese patients with high cardiovascular risk
Yongquan Wu 1Meijing Li 1Jue Li 1Yingyi Luo 1Yan Xing 1Dayi Hu1
作者信息
- 1. Heart,Lung and Blood Vessel Center,Tongji University,Shanghai 200092,China
- 折叠
摘要
Abstract
Objective To assess the predictive value of serum uric acid levels for cardiovascular and all-cause mortality in a large prospective population based study.Methods The study was based on 3648 participants in Shanghai and Beijing,who were inpatients with high cardiovascular(CV) risk at baseLine (2004.7 to 2005.1),and blood was taken.Follow-up for death from cardiovascular disease and any cause was complete until January 1,2006.Results The mean follow-up was 1 years.There were 303 deaths during follow-up,of which 121 were cardiovascular.Crude mortality rates were 8.3 % for all patients,6.8% for female patients (116/1715),and 9.7% (187/1933) for male patients.Among men,patients in the lower and higher uric acid groups had increased cardiac and overall mortality risks compared with patients in the normal uric acid groups.Similar relation was found in women but not statistically significant.After adjusting for other conventional risk factors (age,diabetes,hypertension,diuretic use and smoking),baseline uric acid level was still associated with increased risk for death from cardiovascular disease (P=0.005),or death from all causes (P=0.014) Conclusion Our data suggest that abnormal serum uric acid levels are independently and significantly associated with risk of cardiovascular and all-cause mortality.(J Geriatr Cardiol 2008;5:15-20)关键词
epidemiology/uric acid/cardiovascular mortality /all-cause mortalityKey words
epidemiology/uric acid/cardiovascular mortality /all-cause mortality分类
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Yongquan Wu,Meijing Li,Jue Li,Yingyi Luo,Yan Xing,Dayi Hu..Elevated serum uric acid level as a predictor for cardiovascular and all-cause mortality in Chinese patients with high cardiovascular risk[J].老年心脏病学杂志（英文版）,2008,5(1):15-20,6.
