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黄芪预防术后硬膜外粘连的实验研究

沈权 叶澄宇 侯筱魁

中国骨伤2001,Vol.14Issue(3):152-153,2.
中国骨伤2001,Vol.14Issue(3):152-153,2.

黄芪预防术后硬膜外粘连的实验研究

An experimental study of preventive effects of Huangqi on postoperative peridural adhesion

沈权 1叶澄宇 1侯筱魁2

作者信息

  • 1. 温州医学院附属第一医院,
  • 2. 上海第二医科大学附属第九人民医院,
  • 折叠

摘要

Abstract

Objective To study the effects of Huangqi(Chinese herb)for prevention of peridural adhesion after operation.Methods L2 and L5 laminectomy of 22 New Zealand rabbits were performed in this experimental study.Partial yellow ligament was sectioned and fat was exposed.Then the peridural fat was sectioned.The 44 vertebral lamina seyments were randomly divided into two groups of a. Huangqi group and b.Normal Saline(NS)group.The b group was control group.Huangqi liquid and NS were separately injected into the defect points of L2 and L5 vertebral lamina of the two groups.The speciments were obtained at 2nd,4th and 8th weeks after operation.Optical microscope and transmission electron microscope were used for the observation.Results There were many changes in group a:little migration of inflammation cells,small number of fibroblast and collagen,no adhesion of peridural scar,no degeneration and demyelination of spinal nerves.But in group b,adhesion of peridural scar could be seen clearly.Conclusion Huangqi has no nerve toxicity and it could be used as a good medicine to prevent postoperative peridural adhesion.

关键词

中草药术后并发症组织细胞

分类

医药卫生

引用本文复制引用

沈权,叶澄宇,侯筱魁..黄芪预防术后硬膜外粘连的实验研究[J].中国骨伤,2001,14(3):152-153,2.

中国骨伤

1003-0034

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